ARBORVITAE BIOLOGICS The science of life

Arborvitae Biologics has developed innovative perinatal tissue extractions and processes, which allow our product offerings to be of the highest cellular bioavailability and safety standards. With these safety and quality standards, VitaeShot®, VitaeFlow® and VitaeCyte® are the top perinatal tissue allografts in the field of regenerative medicine.

WHY ARBORVITAE BIOLOGICS?

Our minimally manipulated flowable tissue allograft biologics are comprised of carefully selected, safety tested, perinatal tissue from live, healthy human births. Umbilical Cord tissue with Wharton’s Jelly and Amniotic tissue are meticulously harvested and safely processed to provide optimal outcomes. Our products contain the highest therapeutic quality bio-components, assisting with improved patient outcomes. The proprietary donor tissue screening, harvesting and processing protocols protect and preserve the therapeutic value and set Arborvitae Biologics apart from other products with respect to concentration, bioavailability, efficacy and patient outcomes.

The Benefits of FLOWABLE AMNIOTIC TISSUE

Amniotic tissue flowables promote healing with anti-inflammatory properties (Cytokines & Growth Factors, Exosomes, microRNA, etc) which may limit the development of fibrotic scar tissue formation.  Amnion tissue is micronized into a flowable from Perinatal products resulting from healthy live birthed babies. Amnion Tissue has similar regenerative characteristics as stem cells since it possesses the ability to create a cellular cascade (paracrine signaling) recruiting the bodies own precious stem cells. This means that this cellular cascade either makes new cells that are the same, or they make cells that can change into the type of cell that the body needs, where the body needs it. They can be can be used to treat painful and degenerative conditions requiring homologous graft for purpose of of repair or regeneration. Human amniotic membrane has a profound healing impact on tissue inflammation and fibrosis and is a protective barrier as needed.  Amniotic Fluid alone has similar properties with fewer viable cells.

These graft tissues are shown to be immune privileged, without risk of graft failure or rejection which can lead to fibrosis.

VitaeCyte, a cryopreserved amniotic fluid, Wharton’s jelly, ECM allograft, minimally manipulated via the AnuSureTech proprietary process, maintains the functions of placental tissue containing extracellular matrix and bioactive cytokines (growth factors, chemokines). It is the combination of the amniotic fluid, Wharton’s jelly, and extra-cellular matrix (ECM), cytokines, their immunomodulatory effect and their anti-inflammatory, immunomodulating, tissue regenerative attributes that make their use in regenerative medicine highly effective and safe, providing significant value in pain control, orthopedic pathologies, organ system pathologies.

The bioassay results presented in this paper demonstrate that the AnuSureTech process is a significant advancement in placental tissue processing providing high levels of cytokines, growth factors, cellular components and ECM after processing and sterilization.

THE BENEFITS OF FLOWABLE UMBILICAL CORD TISSUE

The umbilical cord contains an inexhaustible, noncontroversial source of stem cells for therapy. Umbilical Cord Tissue is considered by thought leaders in biomedical research to hold the promise of innovation in regenerative medicine. These sources contain extracellular matrix (ECM) structural healing components, Stem Cells (MSCs) and growth factors for the efficient repair and healing of injured or degenerated tissue through the replacement of cells which are identical to the original tissue.  The cells in the Wharton’s Jelly of the cord contain MSCs (Mesenchymal Stem Cells or Medicinal signaling Cells) and have shown the ability in studies to evolve into tissue cells. The Extracellular Matrix contains a high concentration of collagens, providing an effective biomechanical scaffold, containing various growth factors connective proteins and bioactive molecules.

Due to Wharton’s Jelly MSCs rate of growth, immune-privilege status, non- tumor-making property and lack of ethical concerns, cord tissue is an ideal MSC and stem cell stimulating source.

VITASHOT is coming in 2019

VITAEFLOW is coming in 2019

Producing Quality Products

WE DISTINGUISH OURSELVES

Arborvitae Biologics distinguishes itself in the regenerative medicine industry with a high concentration of therapeutic bio-elements and non invasive processing. Our scientists conduct basic and applied research in the field of Stem Cell Biology with the long-term goal of harnessing the properties of stem cells for regenerative medicine and cell therapy. Our proprietary processing protocols protect and preserve the therapeutic elements from donor tissues and set VitaeShot®, VitaeFlow® and VitaeCyte® apart from competitors’ products with respect to bioavailability, concentration and efficacy. The products are safely and conveniently provided in a cryopreserved state.

IMPROVED PATIENT OUTCOMES

Regenerative Medicine and human tissue based therapies are already improving the lives of patients suffering from damage to tissues resulting from injury, disease, or age. The rapid expansion of scientific knowledge offers great promise for continuing advances in this field of regenerative biologics. As research moves forward, the opportunities for more extensive patient treatments is continuing to grow at a rapid pace daily. Regenerative medicine using perinatal derived products has been growing rapidly and will continue to grow at an amazing pace. More and more physicians are making this new and exciting branch of modern medicine a part of their practices to better serve the needs of their patients. Arborvitae Biologics provides the highest quality products to help improve the lives and well-being of patients through regenerative medicine with the highest, most pure content including Growth Factors, Cytokines, Secretosomes, Exosomes and microRNA.